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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDPK1
All Species:
24.24
Human Site:
Y185
Identified Species:
44.44
UniProt:
O15530
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15530
NP_002604.1
556
63152
Y185
D
E
T
C
T
R
F
Y
T
A
E
I
V
S
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537000
560
63701
Y189
D
E
T
C
T
R
F
Y
T
A
E
M
V
S
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2A0
559
63740
Y188
D
E
T
C
T
R
F
Y
T
A
E
I
V
S
A
Rat
Rattus norvegicus
O55173
559
63591
Y188
D
E
T
C
T
R
F
Y
T
A
E
I
V
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518589
320
36424
Chicken
Gallus gallus
Q6U1I9
432
48872
H118
G
K
V
L
L
A
R
H
K
A
E
E
Q
F
Y
Frog
Xenopus laevis
Q6GPN6
434
49096
H120
G
K
V
L
L
A
R
H
Q
A
D
E
K
F
Y
Zebra Danio
Brachydanio rerio
Q7ZTW4
433
48964
H119
G
K
V
L
L
A
R
H
R
S
D
E
K
F
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W0V1
836
94060
Y350
D
V
A
C
T
R
H
Y
A
A
E
L
L
L
A
Honey Bee
Apis mellifera
XP_394208
537
61368
V185
L
L
D
E
K
M
H
V
L
I
T
D
F
G
S
Nematode Worm
Caenorhab. elegans
Q9Y1J3
636
71898
F177
D
M
L
T
S
K
F
F
A
S
E
I
L
T
G
Sea Urchin
Strong. purpuratus
XP_786576
539
61612
Y187
D
E
S
S
S
R
F
Y
T
S
E
I
I
L
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12236
1081
121642
Y283
D
E
T
C
A
R
Y
Y
A
A
Q
I
I
D
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
93.3
N.A.
94.8
95.3
N.A.
52.1
28.6
28
27.5
N.A.
32.5
54.1
32.5
58
Protein Similarity:
100
N.A.
N.A.
95
N.A.
96.2
96.4
N.A.
54.6
44
43.8
43.3
N.A.
44.1
66.1
52.2
70.3
P-Site Identity:
100
N.A.
N.A.
93.3
N.A.
100
100
N.A.
0
13.3
6.6
0
N.A.
53.3
0
26.6
60
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
0
26.6
26.6
26.6
N.A.
66.6
6.6
66.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
24
0
0
24
62
0
0
0
0
54
% A
% Cys:
0
0
0
47
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
62
0
8
0
0
0
0
0
0
0
16
8
0
8
0
% D
% Glu:
0
47
0
8
0
0
0
0
0
0
62
24
0
0
0
% E
% Phe:
0
0
0
0
0
0
47
8
0
0
0
0
8
24
0
% F
% Gly:
24
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% G
% His:
0
0
0
0
0
0
16
24
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
0
47
16
0
0
% I
% Lys:
0
24
0
0
8
8
0
0
8
0
0
0
16
0
0
% K
% Leu:
8
8
8
24
24
0
0
0
8
0
0
8
16
16
0
% L
% Met:
0
8
0
0
0
8
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
8
0
8
0
0
% Q
% Arg:
0
0
0
0
0
54
24
0
8
0
0
0
0
0
0
% R
% Ser:
0
0
8
8
16
0
0
0
0
24
0
0
0
31
8
% S
% Thr:
0
0
39
8
39
0
0
0
39
0
8
0
0
8
0
% T
% Val:
0
8
24
0
0
0
0
8
0
0
0
0
31
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
54
0
0
0
0
0
0
24
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _